Contracting a disease on holiday may ruin your trip and have severe financial implications. Some diseases may also cause you to develop a long-term debilitating illness and may even be life-threatening. The protection needed for your trip will depend greatly on your planned destination and itinerary.If you plan to travel to a country where exposure to disease is likely, or you intend to camp, stay in hotels or visit rural areas, you will probably need to be vaccinated.